Searchable abstracts of presentations at key conferences in endocrinology

ea0065oc4.4 | Thyroid | SFEBES2019

Development of auto-immune thyroid dysfunction in multiple sclerosis patients receiving Alemtuzumab is associated with improved response to treatment

Sovetkina Alina , Nicholas Richard , Malik Omar , Tona Francesca , Dorsey Rachel , Scalfari Antonio , Rigoni Eleonora , Nandoskar Ashwini , Singh-Curry Victoria , Martin Niamh

Background: Alemtuzumab is an anti-CD52 monoclonal antibody used in the treatment of relapsing-remitting multiple sclerosis (MS). Between 20 and 40% of Alemtuzumab-treated MS patients develop autoimmune thyroid disease (AITD) as a side effect. It is currently unknown whether development of AITD correlates with MS disease activity following Alemtuzumab treatment.Aims: To characterise the types and frequency of AITD that MS patients develop following Alemt...